Difference between revisions of "YOR138C"
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| − | '''Description of YOR138C:''' Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; | + | '''Description of YOR138C:''' Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; has a WW domain consensus motif of PPPSY (residues 131-135) that mediates binding of Rsp5p to Ubp2p; contains an UBA domain<ref name='S000129012'>Lam MH, et al. (2009) Interaction of the Deubiquitinating Enzyme Ubp2 and the E3 Ligase Rsp5 Is Required for Transporter/Receptor Sorting in the Multivesicular Body Pathway. PLoS ONE 4(1):e4259 {{SGDpaper|S000129012}} PMID 19165343</ref><ref name='S000081856'>Kee Y, et al. (2005) The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme. EMBO J 24(13):2414-24 |
{{SGDpaper|S000081856}} PMID 15933713</ref> | {{SGDpaper|S000081856}} PMID 15933713</ref> | ||
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Revision as of 13:05, 27 February 2009
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| Systematic name | YOR138C |
| Gene name | RUP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:586325..584310 |
| Primary SGDID | S000005664 |
Description of YOR138C: Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; has a WW domain consensus motif of PPPSY (residues 131-135) that mediates binding of Rsp5p to Ubp2p; contains an UBA domain[1][2]
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References
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- ↑ Lam MH, et al. (2009) Interaction of the Deubiquitinating Enzyme Ubp2 and the E3 Ligase Rsp5 Is Required for Transporter/Receptor Sorting in the Multivesicular Body Pathway. PLoS ONE 4(1):e4259 SGD PMID 19165343
- ↑ Kee Y, et al. (2005) The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme. EMBO J 24(13):2414-24 SGD PMID 15933713
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