Difference between revisions of "YNR031C"
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| − | '''Description of YNR031C:''' MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress<ref name=' | + | '''Description of YNR031C:''' MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress<ref name='S000056287'>Posas F and Saito H (1998) Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator. EMBO J 17(5):1385-94 {{SGDpaper|S000056287}} PMID 9482735</ref><ref name='S000070407'>Yuzyuk T, et al. (2002) The MEK kinase Ssk2p promotes actin cytoskeleton recovery after osmotic stress. Mol Biol Cell 13(8):2869-80 {{SGDpaper|S000070407}} PMID 12181352</ref><ref name='S000074029'>Tatebayashi K, et al. (2003) A docking site determining specificity of Pbs2 MAPKK for Ssk2/Ssk22 MAPKKKs in the yeast HOG pathway. EMBO J 22(14):3624-34 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074029}} PMID 12853477</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YNR031C |
| Gene name | SSK2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:685435..680696 |
| Primary SGDID | S000005314 |
Description of YNR031C: MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress[1][2][3]
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References
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- ↑ Posas F and Saito H (1998) Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator. EMBO J 17(5):1385-94 SGD PMID 9482735
- ↑ Yuzyuk T, et al. (2002) The MEK kinase Ssk2p promotes actin cytoskeleton recovery after osmotic stress. Mol Biol Cell 13(8):2869-80 SGD PMID 12181352
- ↑ Tatebayashi K, et al. (2003) A docking site determining specificity of Pbs2 MAPKK for Ssk2/Ssk22 MAPKKKs in the yeast HOG pathway. EMBO J 22(14):3624-34 SGD PMID 12853477
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