Difference between revisions of "YNL262W"
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| − | '''Description of YNL262W:''' Catalytic subunit of DNA polymerase epsilon, | + | '''Description of YNL262W:''' Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p<ref name='S000128058'>Lou H, et al. (2008) Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint. Mol Cell 32(1):106-17 {{SGDpaper|S000128058}} PMID 18851837</ref><ref name='S000071469'>Shimizu K, et al. (2002) Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae. J Biol Chem 277(40):37422-9 {{SGDpaper|S000071469}} PMID 12124389</ref><ref name='S000058372'>Burgers PM (1998) Eukaryotic DNA polymerases in DNA replication and DNA repair. Chromosoma 107(4):218-27 |
{{SGDpaper|S000058372}} PMID 9745046</ref> | {{SGDpaper|S000058372}} PMID 9745046</ref> | ||
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Revision as of 06:21, 26 February 2009
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| Systematic name | YNL262W |
| Gene name | POL2 |
| Aliases | DUN2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:148213..154881 |
| Primary SGDID | S000005206 |
Description of YNL262W: Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p[1][2][3]
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References
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- ↑ Lou H, et al. (2008) Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint. Mol Cell 32(1):106-17 SGD PMID 18851837
- ↑ Shimizu K, et al. (2002) Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae. J Biol Chem 277(40):37422-9 SGD PMID 12124389
- ↑ Burgers PM (1998) Eukaryotic DNA polymerases in DNA replication and DNA repair. Chromosoma 107(4):218-27 SGD PMID 9745046
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