Difference between revisions of "YNL158W"

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'''Description of YNL158W:''' Essential protein required for maturation of Gas1p and Pho8p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery; has synthetic genetic interations with secretory pathway genes<ref name='S000086691'>Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 {{SGDpaper|S000086691}} PMID 16155567</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
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'''Description of YNL158W:''' Essential component of GPI-mannosyltransferase II, responsible for second mannose addition to GPI precursors as a partner of Gpi18p; required for maturation of Gas1p and Pho8p; has synthetic genetic interations with secretory pathway genes<ref name='S000123227'>Sato K, et al. (2007) Pga1 Is an Essential Component of Glycosylphosphatidylinositol-Mannosyltransferase II of Saccharomyces cerevisiae. Mol Biol Cell 18(9):3472-85 {{SGDpaper|S000123227}} PMID 17615295</ref><ref name='S000086691'>Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 {{SGDpaper|S000086691}} PMID 16155567</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
 
  {{SGDpaper|S000071347}} PMID 12140549</ref>
 
  {{SGDpaper|S000071347}} PMID 12140549</ref>
 
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Revision as of 06:21, 26 February 2009

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Systematic name YNL158W
Gene name PGA1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:339614..340210
Primary SGDID S000005102


Description of YNL158W: Essential component of GPI-mannosyltransferase II, responsible for second mannose addition to GPI precursors as a partner of Gpi18p; required for maturation of Gas1p and Pho8p; has synthetic genetic interations with secretory pathway genes[1][2][3][4]




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References

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  1. Sato K, et al. (2007) Pga1 Is an Essential Component of Glycosylphosphatidylinositol-Mannosyltransferase II of Saccharomyces cerevisiae. Mol Biol Cell 18(9):3472-85 SGD PMID 17615295
  2. Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 SGD PMID 16155567
  3. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  4. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549

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