Difference between revisions of "YNL062C"
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| − | '''Description of YNL062C:''' Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression<ref name=' | + | '''Description of YNL062C:''' Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression<ref name='S000049268'>Anderson J, et al. (2000) The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 97(10):5173-8 {{SGDpaper|S000049268}} PMID 10779558</ref><ref name='S000050613'>Anderson J, et al. (1998) The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. Genes Dev 12(23):3650-62 {{SGDpaper|S000050613}} PMID 9851972</ref><ref name='S000066074'>Hinnebusch A (1992) General and Pathway-specific Regulatory Mechanisms Controlling the Synthesis of Amino Acid Biosynthetic Enzymes in Saccharomyces cerevisiae. Pp. 319-414 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press |
| − | {{SGDpaper| | + | {{SGDpaper|S000066074}} PMID </ref> |
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Revision as of 13:05, 31 March 2009
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| Systematic name | YNL062C |
| Gene name | GCD10 |
| Aliases | TRM6 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:510213..508777 |
| Primary SGDID | S000005006 |
Description of YNL062C: Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression[1][2][3]
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References
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- ↑ Anderson J, et al. (2000) The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 97(10):5173-8 SGD PMID 10779558
- ↑ Anderson J, et al. (1998) The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA. Genes Dev 12(23):3650-62 SGD PMID 9851972
- ↑ Hinnebusch A (1992) General and Pathway-specific Regulatory Mechanisms Controlling the Synthesis of Amino Acid Biosynthetic Enzymes in Saccharomyces cerevisiae. Pp. 319-414 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
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