Difference between revisions of "YMR004W"
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| − | '''Description of YMR004W:''' Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole<ref name='S000051863'>Ekena K and Stevens TH (1995) The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting. Mol Cell Biol 15(3):1671-8 | + | '''Description of YMR004W:''' Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole; participates in transcription initiation and/or early elongation of specific genes; interacts with "foot domain" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions<ref name='S000051863'>Ekena K and Stevens TH (1995) The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting. Mol Cell Biol 15(3):1671-8 {{SGDpaper|S000051863}} PMID 7862158</ref><ref name='S000146910'>Garcia-Lopez MC, et al. (2011) The Conserved Foot Domain of RNA Pol II Associates with Proteins Involved in Transcriptional Initiation and/or Early Elongation. Genetics () |
| − | {{SGDpaper| | + | {{SGDpaper|S000146910}} PMID 21954159</ref> |
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Revision as of 14:05, 5 October 2011
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| Systematic name | YMR004W |
| Gene name | MVP1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:274017..275552 |
| Primary SGDID | S000004606 |
Description of YMR004W: Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole; participates in transcription initiation and/or early elongation of specific genes; interacts with "foot domain" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions[1][2]
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References
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- Jump up ↑ Ekena K and Stevens TH (1995) The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting. Mol Cell Biol 15(3):1671-8 SGD PMID 7862158
- Jump up ↑ Garcia-Lopez MC, et al. (2011) The Conserved Foot Domain of RNA Pol II Associates with Proteins Involved in Transcriptional Initiation and/or Early Elongation. Genetics () SGD PMID 21954159
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