Difference between revisions of "YLR386W"
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− | '''Description of YLR386W:''' Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p<ref name=' | + | '''Description of YLR386W:''' Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p<ref name='S000069781'>Bonangelino CJ, et al. (2002) Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J Cell Biol 156(6):1015-28 {{SGDpaper|S000069781}} PMID 11889142</ref><ref name='S000071861'>Dove SK, et al. (2002) Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body. Curr Biol 12(11):885-93 {{SGDpaper|S000071861}} PMID 12062051</ref><ref name='S000074437'>Rudge SA, et al. (2004) Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Mol Biol Cell 15(1):24-36 |
− | {{SGDpaper| | + | {{SGDpaper|S000074437}} PMID 14528018</ref> |
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Revision as of 14:05, 31 March 2009
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Systematic name | YLR386W |
Gene name | VAC14 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XII:893628..896270 |
Primary SGDID | S000004378 |
Description of YLR386W: Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p[1][2][3]
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References
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- ↑ Bonangelino CJ, et al. (2002) Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J Cell Biol 156(6):1015-28 SGD PMID 11889142
- ↑ Dove SK, et al. (2002) Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body. Curr Biol 12(11):885-93 SGD PMID 12062051
- ↑ Rudge SA, et al. (2004) Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Mol Biol Cell 15(1):24-36 SGD PMID 14528018
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