Difference between revisions of "YER068W"

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==Community Commentary==
 
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==References==
 
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Revision as of 07:17, 30 January 2007

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Systematic name YER068W
Gene name MOT2
Aliases NOT4, SIG1
Feature type ORF, Verified
Coordinates Chr V:293048..294811


Description of YER068W: Component of the CCR4-NOT complex, which has multiple roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitylates subunits of the nascent polypeptide-associated complex (NAC)[1][2][3][4][5]




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Community Commentary

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References

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  1. Panasenko O, et al. (2006) The Yeast Ccr4-Not Complex Controls Ubiquitination of the Nascent-associated Polypeptide (NAC-EGD) Complex. J Biol Chem 281(42):31389-98 SGD PMID 16926149
  2. Denis CL, et al. (2001) Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation. Genetics 158(2):627-34 SGD PMID 11404327
  3. Badarinarayana V, et al. (2000) Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. Genetics 155(3):1045-54 SGD PMID 10880468
  4. Liu HY, et al. (1998) The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively. EMBO J 17(4):1096-106 SGD PMID 9463387
  5. Bai Y, et al. (1999) The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5. Mol Cell Biol 19(10):6642-51 SGD PMID 10490603

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