Difference between revisions of "YGL136C"
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| − | '''Description of YGL136C:''' Mitochondrial | + | '''Description of YGL136C:''' Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ<ref name='S000075306'>Bonnerot C, et al. (2003) Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Mol Cell 12(5):1309-15 {{SGDpaper|S000075306}} PMID 14636587</ref><ref name='S000069245'>Pintard L, et al. (2002) MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase. EMBO J 21(5):1139-47 |
{{SGDpaper|S000069245}} PMID 11867542</ref> | {{SGDpaper|S000069245}} PMID 11867542</ref> | ||
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Revision as of 13:05, 13 August 2007
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| Systematic name | YGL136C |
| Gene name | MRM2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:253864..252902 |
| Primary SGDID | S000003104 |
Description of YGL136C: Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ[1][2]
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References
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- ↑ Bonnerot C, et al. (2003) Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Mol Cell 12(5):1309-15 SGD PMID 14636587
- ↑ Pintard L, et al. (2002) MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase. EMBO J 21(5):1139-47 SGD PMID 11867542
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