Difference between revisions of "YDR517W"

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'''Description of YDR517W:''' Protein involved in the spindle assembly checkpoint; homolog of human GRASP65, which is a Golgi localized protein that functions in postmitotic reassembly of Golgi stacks<ref name='S000072519'>Norman TC, et al. (1999) Genetic selection of peptide inhibitors of biological pathways. Science 285(5427):591-5
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'''Description of YDR517W:''' Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes<ref name='S000120685'>Behnia R, et al. (2007) The yeast orthologue of GRASP65 forms a complex with a coiled-coil protein that contributes to ER to Golgi traffic. J Cell Biol 176(3):255-61 {{SGDpaper|S000120685}} PMID 17261844</ref><ref name='S000072519'>Norman TC, et al. (1999) Genetic selection of peptide inhibitors of biological pathways. Science 285(5427):591-5
 
  {{SGDpaper|S000072519}} PMID 10417390</ref>
 
  {{SGDpaper|S000072519}} PMID 10417390</ref>
 
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Revision as of 13:05, 5 June 2007

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Systematic name YDR517W
Gene name GRH1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1477231..1478349
Primary SGDID S000002925


Description of YDR517W: Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes[1][2]




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References

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  1. Behnia R, et al. (2007) The yeast orthologue of GRASP65 forms a complex with a coiled-coil protein that contributes to ER to Golgi traffic. J Cell Biol 176(3):255-61 SGD PMID 17261844
  2. Norman TC, et al. (1999) Genetic selection of peptide inhibitors of biological pathways. Science 285(5427):591-5 SGD PMID 10417390

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