Difference between revisions of "YDL142C"

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'''Description of YDL142C:''' Cardiolipin synthase; produces cardiolipin, which is an important constituent of mitochondrial membranes; required for normal mitochondrial membrane potential and function<ref name='S000074003'>Zhang M, et al. (2003) Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures. J Biol Chem 278(37):35204-10 {{SGDpaper|S000074003}} PMID 12840009</ref><ref name='S000054155'>Jiang F, et al. (1999) Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development. Mol Microbiol 31(1):373-9 {{SGDpaper|S000054155}} PMID 9987137</ref><ref name='S000045719'>Jiang F, et al. (2000) Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J Biol Chem 275(29):22387-94 {{SGDpaper|S000045719}} PMID 10777514</ref><ref name='S000043519'>Chang SC, et al. (1998) Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae. J Biol Chem 273(24):14933-41
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'''Description of YDL142C:''' Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis<ref name='S000127786'>Chen S, et al. (2008) Cardiolipin Mediates Cross-Talk between Mitochondria and the Vacuole. Mol Biol Cell  {{SGDpaper|S000127786}} PMID 18799619</ref><ref name='S000074003'>Zhang M, et al. (2003) Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures. J Biol Chem 278(37):35204-10 {{SGDpaper|S000074003}} PMID 12840009</ref><ref name='S000054155'>Jiang F, et al. (1999) Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development. Mol Microbiol 31(1):373-9 {{SGDpaper|S000054155}} PMID 9987137</ref><ref name='S000045719'>Jiang F, et al. (2000) Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J Biol Chem 275(29):22387-94 {{SGDpaper|S000045719}} PMID 10777514</ref><ref name='S000043519'>Chang SC, et al. (1998) Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae. J Biol Chem 273(24):14933-41
 
  {{SGDpaper|S000043519}} PMID 9614098</ref>
 
  {{SGDpaper|S000043519}} PMID 9614098</ref>
 
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Revision as of 13:05, 1 October 2008

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Systematic name YDL142C
Gene name CRD1
Aliases CLS1
Feature type ORF, Verified
Coordinates Chr IV:202571..201720
Primary SGDID S000002301


Description of YDL142C: Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis[1][2][3][4][5]




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References

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  1. Chen S, et al. (2008) Cardiolipin Mediates Cross-Talk between Mitochondria and the Vacuole. Mol Biol Cell SGD PMID 18799619
  2. Zhang M, et al. (2003) Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures. J Biol Chem 278(37):35204-10 SGD PMID 12840009
  3. Jiang F, et al. (1999) Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development. Mol Microbiol 31(1):373-9 SGD PMID 9987137
  4. Jiang F, et al. (2000) Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J Biol Chem 275(29):22387-94 SGD PMID 10777514
  5. Chang SC, et al. (1998) Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae. J Biol Chem 273(24):14933-41 SGD PMID 9614098

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