Difference between revisions of "YEL031W"
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| + | === Alleles, Strains, and Phenotypes === | ||
| + | [[Category:Topic:Alleles, Strains, and Phenotypes]] | ||
| + | ==== Complete Deletion ==== | ||
| + | [[Category:Topic:Alleles, Strains, and Phenotypes:Complete Deletion]] | ||
| + | '''Genotype''': RHY1202<br> | ||
| + | '''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]], Recessive [[Category:Phenotype:Recessive]], Viable [[Category:Phenotype:Viable]] | ||
| + | Deletion of COD1/SPF1 prevents the degradation of Hmg2p from being regulated. <ref name='S000051798'>Cronin SR, et al. (2000) Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J Cell Biol 148(5):915-24 {{SGDpaper|S000051798}} PMID 10704442</ref> <ref name = 'CAset1165-2003-06-13'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=1165 Stephen R. Cronin] on 2003-06-13</ref> | ||
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| + | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | === Alleles, Strains, and Phenotypes === | ||
| + | [[Category:Topic:Alleles, Strains, and Phenotypes]] | ||
| + | ==== Complete Deletion ==== | ||
| + | [[Category:Topic:Alleles, Strains, and Phenotypes:Complete Deletion]] | ||
| + | '''Genotype''': RHY1202<br> | ||
| + | '''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]], Recessive [[Category:Phenotype:Recessive]], Viable [[Category:Phenotype:Viable]] | ||
| + | |||
| + | Deletion of COD1/SPF1 prevents the degradation of Hmg2p from being regulated. <ref name='S000051798'>Cronin SR, et al. (2000) Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J Cell Biol 148(5):915-24 {{SGDpaper|S000051798}} PMID 10704442</ref> <ref name = 'CAset1165-2003-06-13'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=1165 Stephen R. Cronin] on 2003-06-13</ref> | ||
| + | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
Revision as of 16:05, 23 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YEL031W | |
| Gene name | SPF1 | |
| Aliases | COD1, PER9, PIO1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr V:90258..93905 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YEL031W: P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1[1][2][3]
Alleles, Strains, and Phenotypes
Complete Deletion
Genotype: RHY1202
Phenotype(s): Loss of function (Null), Recessive, Viable
Deletion of COD1/SPF1 prevents the degradation of Hmg2p from being regulated. [2] [4]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Alleles, Strains, and Phenotypes
Complete Deletion
Genotype: RHY1202
Phenotype(s): Loss of function (Null), Recessive, Viable
Deletion of COD1/SPF1 prevents the degradation of Hmg2p from being regulated. [2] [4]
References
See Help:References on how to add references
- ↑ Cronin SR, et al. (2002) Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis. J Cell Biol 157(6):1017-28 SGD PMID 12058017
- ↑ 2.0 2.1 2.2 Cronin SR, et al. (2000) Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J Cell Biol 148(5):915-24 SGD PMID 10704442
- ↑ Suzuki C and Shimma YI (1999) P-type ATPase spf1 mutants show a novel resistance mechanism for the killer toxin SMKT. Mol Microbiol 32(4):813-23 SGD PMID 10361284
- ↑ 4.0 4.1 submitted by Stephen R. Cronin on 2003-06-13
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