Difference between revisions of "YER021W"
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− | '''Description of YER021W:''' Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control<ref name=' | + | '''Description of YER021W:''' Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control<ref name='S000039974'>Glickman MH, et al. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94(5):615-23 {{SGDpaper|S000039974}} PMID 9741626</ref><ref name='S000042175'>Bailly E and Reed SI (1999) Functional characterization of rpn3 uncovers a distinct 19S proteasomal subunit requirement for ubiquitin-dependent proteolysis of cell cycle regulatory proteins in budding yeast. Mol Cell Biol 19(10):6872-90 {{SGDpaper|S000042175}} PMID 10490625</ref><ref name='S000053581'>Kominami K, et al. (1997) Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1. Mol Biol Cell 8(1):171-87 {{SGDpaper|S000053581}} PMID 9017604</ref><ref name='S000054457'>Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev 13(9):1190-202 |
− | {{SGDpaper| | + | {{SGDpaper|S000054457}} PMID 10323869</ref> |
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Revision as of 04:40, 18 December 2008
Share your knowledge...Edit this entry! <protect>
Systematic name | YER021W |
Gene name | RPN3 |
Aliases | SUN2 |
Feature type | ORF, Verified |
Coordinates | Chr V:196947..198518 |
Primary SGDID | S000000823 |
Description of YER021W: Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control[1][2][3][4]
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References
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- ↑ Glickman MH, et al. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94(5):615-23 SGD PMID 9741626
- ↑ Bailly E and Reed SI (1999) Functional characterization of rpn3 uncovers a distinct 19S proteasomal subunit requirement for ubiquitin-dependent proteolysis of cell cycle regulatory proteins in budding yeast. Mol Cell Biol 19(10):6872-90 SGD PMID 10490625
- ↑ Kominami K, et al. (1997) Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1. Mol Biol Cell 8(1):171-87 SGD PMID 9017604
- ↑ Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev 13(9):1190-202 SGD PMID 10323869
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