Difference between revisions of "YDR310C"
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+ | === Interactions === | ||
+ | [[Category:Topic:Interactions]] | ||
+ | ==== Physical ==== | ||
+ | [[Category:Topic:Interactions:Physical]] | ||
+ | Physical interaction with Hst1 [[Category:Physical Interactions with Hst1]]<br> | ||
+ | Sum1, a repressor of middle meiotic genes, was found to interact with Hst1 by coimmunoprecipitation. A neomorphic allele of Sum1 (Sum1-1) also interacts with Hst1. Hst1 is a histone deacetylase, and it is required for repression of some Sum1 targets. <ref name='S000060164'>Rusche LN and Rine J (2001) Conversion of a gene-specific repressor to a regional silencer. Genes Dev 15(8):955-67 {{SGDpaper|S000060164}} PMID 11316790</ref> <ref name = 'CAset9199-2003-03-14'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9199 Hunter Fraser] on 2003-03-14</ref> | ||
+ | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
+ | === Interactions === | ||
+ | [[Category:Topic:Interactions]] | ||
+ | ==== Physical ==== | ||
+ | [[Category:Topic:Interactions:Physical]] | ||
+ | Physical interaction with Hst1 [[Category:Physical Interactions with Hst1]]<br> | ||
+ | Sum1, a repressor of middle meiotic genes, was found to interact with Hst1 by coimmunoprecipitation. A neomorphic allele of Sum1 (Sum1-1) also interacts with Hst1. Hst1 is a histone deacetylase, and it is required for repression of some Sum1 targets. <ref name='S000060164'>Rusche LN and Rine J (2001) Conversion of a gene-specific repressor to a regional silencer. Genes Dev 15(8):955-67 {{SGDpaper|S000060164}} PMID 11316790</ref> <ref name = 'CAset9199-2003-03-14'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9199 Hunter Fraser] on 2003-03-14</ref> | ||
+ | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
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Revision as of 17:05, 23 January 2007
Share your knowledge...Edit this entry!
Systematic name | YDR310C | |
Gene name | SUM1 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr IV:1084312..1081124 | |
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Description of YDR310C: Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; involved in telomere maintenance, regulated by the pachytene checkpoint[1][2][3][4][5]
Interactions
Physical
Physical interaction with Hst1
Sum1, a repressor of middle meiotic genes, was found to interact with Hst1 by coimmunoprecipitation. A neomorphic allele of Sum1 (Sum1-1) also interacts with Hst1. Hst1 is a histone deacetylase, and it is required for repression of some Sum1 targets. [6] [7]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Physical
Physical interaction with Hst1
Sum1, a repressor of middle meiotic genes, was found to interact with Hst1 by coimmunoprecipitation. A neomorphic allele of Sum1 (Sum1-1) also interacts with Hst1. Hst1 is a histone deacetylase, and it is required for repression of some Sum1 targets. [6] [7]
References
See Help:References on how to add references
- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
- ↑ Lindgren A, et al. (2000) The pachytene checkpoint in Saccharomyces cerevisiae requires the Sum1 transcriptional repressor. EMBO J 19(23):6489-97 SGD PMID 11101521
- ↑ Laurenson P and Rine J (1991) SUM1-1: a suppressor of silencing defects in Saccharomyces cerevisiae. Genetics 129(3):685-96 SGD PMID 1752414
- ↑ Klar AJ, et al. (1985) SUM1, an apparent positive regulator of the cryptic mating-type loci in Saccharomyces cerevisiae. Genetics 111(4):745-58 SGD PMID 3905506
- ↑ Xie J, et al. (1999) Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae. EMBO J 18(22):6448-54 SGD PMID 10562556
- ↑ 6.0 6.1 Rusche LN and Rine J (2001) Conversion of a gene-specific repressor to a regional silencer. Genes Dev 15(8):955-67 SGD PMID 11316790
- ↑ 7.0 7.1 submitted by Hunter Fraser on 2003-03-14
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