Difference between revisions of "YOR076C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005602 YOR076C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SKI7 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SKI7 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XV:471622..469379 | |nowrap| Chr XV:471622..469379 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005602 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YOR076C:''' Antiviral adaptor protein that mediates interactions via its N-terminus between the exosome and Ski complex (Ski2p, Ski3p, Ski8p) which operate in the 3'-to-5' mRNA-decay pathway; cytoplasmic protein required for degrading nonstop mRNAs<ref name='S000073211'>Sheth U and Parker R (2003) Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300(5620):805-8 {{SGDpaper|S000073211}} PMID 12730603</ref><ref name='S000069566'>van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 {{SGDpaper|S000069566}} PMID 11910110</ref><ref name='S000066048'>Araki Y, et al. (2001) Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast. EMBO J 20(17):4684-93 {{SGDpaper|S000066048}} PMID 11532933</ref><ref name='S000059193'>van Hoof A, et al. (2000) Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA. Mol Cell Biol 20(21):8230-43 {{SGDpaper|S000059193}} PMID 11027292</ref><ref name='S000054260'>Ridley SP, et al. (1984) Superkiller mutations in Saccharomyces cerevisiae suppress exclusion of M2 double-stranded RNA by L-A-HN and confer cold sensitivity in the presence of M and L-A-HN. Mol Cell Biol 4(4):761-70 {{SGDpaper|S000054260}} PMID 6371496</ref><ref name='S000052117'>Benard L, et al. (1999) The ski7 antiviral protein is an EF1-alpha homolog that blocks expression of non-Poly(A) mRNA in Saccharomyces cerevisiae. J Virol 73(4):2893-900 {{SGDpaper|S000052117}} PMID 10074137</ref><ref name='S000042674'>Peltz SW, et al. (1999) Ribosomal protein L3 mutants alter translational fidelity and promote rapid loss of the yeast killer virus. Mol Cell Biol 19(1):384-91 |
{{SGDpaper|S000042674}} PMID 9858562</ref> | {{SGDpaper|S000042674}} PMID 9858562</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOR076C |
| Gene name | SKI7 |
| Aliases | YOR29-27 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:471622..469379 |
| Primary SGDID | S000005602 |
Description of YOR076C: Antiviral adaptor protein that mediates interactions via its N-terminus between the exosome and Ski complex (Ski2p, Ski3p, Ski8p) which operate in the 3'-to-5' mRNA-decay pathway; cytoplasmic protein required for degrading nonstop mRNAs[1][2][3][4][5][6][7]
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Contents
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References
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- ↑ Sheth U and Parker R (2003) Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300(5620):805-8 SGD PMID 12730603
- ↑ van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 SGD PMID 11910110
- ↑ Araki Y, et al. (2001) Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast. EMBO J 20(17):4684-93 SGD PMID 11532933
- ↑ van Hoof A, et al. (2000) Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA. Mol Cell Biol 20(21):8230-43 SGD PMID 11027292
- ↑ Ridley SP, et al. (1984) Superkiller mutations in Saccharomyces cerevisiae suppress exclusion of M2 double-stranded RNA by L-A-HN and confer cold sensitivity in the presence of M and L-A-HN. Mol Cell Biol 4(4):761-70 SGD PMID 6371496
- ↑ Benard L, et al. (1999) The ski7 antiviral protein is an EF1-alpha homolog that blocks expression of non-Poly(A) mRNA in Saccharomyces cerevisiae. J Virol 73(4):2893-900 SGD PMID 10074137
- ↑ Peltz SW, et al. (1999) Ribosomal protein L3 mutants alter translational fidelity and promote rapid loss of the yeast killer virus. Mol Cell Biol 19(1):384-91 SGD PMID 9858562
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