Difference between revisions of "YNR057C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005340 YNR057C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''BIO4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''BIO4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIV:734069..733356 | |nowrap| Chr XIV:734069..733356 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005340 | ||
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| − | '''Description of | + | '''Description of YNR057C:''' Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels<ref name='S000075799'>Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43 {{SGDpaper|S000075799}} PMID 14668481</ref><ref name='S000055833'>Phalip V, et al. (1999) Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake. Gene 232(1):43-51 |
{{SGDpaper|S000055833}} PMID 10333520</ref> | {{SGDpaper|S000055833}} PMID 10333520</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNR057C |
| Gene name | BIO4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:734069..733356 |
| Primary SGDID | S000005340 |
Description of YNR057C: Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels[1][2]
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Community Commentary
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Other
Gene Origin
Horizontally transferred from alpha proteobacteria [3] [4]
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References
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- ↑ Shakoury-Elizeh M, et al. (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15(3):1233-43 SGD PMID 14668481
- ↑ Phalip V, et al. (1999) Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake. Gene 232(1):43-51 SGD PMID 10333520
- ↑ Hall C, et al. (2005) Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryot Cell 4(6):1102-15 SGD PMID 15947202
- ↑ submitted by Charles Hall on 2006-06-09
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