Difference between revisions of "YML060W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004525 YML060W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''OGG1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''OGG1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIII:151871..153001 | |nowrap| Chr XIII:151871..153001 | ||
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+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004525 | ||
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<br> | <br> | ||
− | '''Description of | + | '''Description of YML060W:''' Mitochondrial glycosylase/lyase that specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA<ref name='S000059916'>Singh KK, et al. (2001) Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants. Nucleic Acids Res 29(6):1381-8 {{SGDpaper|S000059916}} PMID 11239005</ref><ref name='S000047535'>Sandigursky M, et al. (1997) The yeast 8-oxoguanine DNA glycosylase (Ogg1) contains a DNA deoxyribophosphodiesterase (dRpase) activity. Nucleic Acids Res 25(22):4557-61 {{SGDpaper|S000047535}} PMID 9358166</ref><ref name='S000046294'>van der Kemp PA, et al. (1996) Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine. Proc Natl Acad Sci U S A 93(11):5197-202 {{SGDpaper|S000046294}} PMID 8643552</ref><ref name='S000046177'>Nash HM, et al. (1996) Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. Curr Biol 6(8):968-80 |
{{SGDpaper|S000046177}} PMID 8805338</ref> | {{SGDpaper|S000046177}} PMID 8805338</ref> | ||
<br> | <br> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
Systematic name | YML060W |
Gene name | OGG1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XIII:151871..153001 |
Primary SGDID | S000004525 |
Description of YML060W: Mitochondrial glycosylase/lyase that specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA[1][2][3][4]
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References
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- ↑ Singh KK, et al. (2001) Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants. Nucleic Acids Res 29(6):1381-8 SGD PMID 11239005
- ↑ Sandigursky M, et al. (1997) The yeast 8-oxoguanine DNA glycosylase (Ogg1) contains a DNA deoxyribophosphodiesterase (dRpase) activity. Nucleic Acids Res 25(22):4557-61 SGD PMID 9358166
- ↑ van der Kemp PA, et al. (1996) Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine. Proc Natl Acad Sci U S A 93(11):5197-202 SGD PMID 8643552
- ↑ Nash HM, et al. (1996) Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. Curr Biol 6(8):968-80 SGD PMID 8805338
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