Positions in yeast labs

Postdoc Position in Ubiquitination and Stress Response at Duke University (posted 08 November 2017)

Description: A post-doctoral research position is available in Dr. Gustavo Silva’s laboratory at Duke University (https://sites.duke.edu/silvalab). The prospective candidate will develop research focused on understanding the role of protein ubiquitination and protein dynamics during cellular response to stress. The lab uses a combination of molecular and large scale approaches, including mass spectrometry-based proteomics and next generation sequencing, to elucidate signaling pathways in yeast and mammalian cells.

Candidate: We are seeking a highly motivated candidate with strong expertise in molecular cloning, recombinant protein, and yeast genetics to fulfill this position. Additional experience in proteomics, genomics, and/or computational biology will be favored and is desirable, but not a requirement. Communication and interpersonal skills are valued in order to work in a young, dynamic, diverse, and collaborative environment

How to apply:Prospective candidates should submit a cover letter describing their research experience, scientific interest, career goals, and motivation to apply for this position. Please include an updated CV and the contact information of three references. Questions should be directed to Dr. Silva at gustavo.silva@duke.edu and applications must be submitted via Academic Jobs Online: https://academicjobsonline.org/ajo/jobs/10359

Postdoc Opening - Autophagy of lipid droplets in YEAST (posted 29 August 2017)

Postdoctoral project: Autophagy of lipid droplets in YEAST

Academic institution: University of California, San Diego

Academic division: Division of Biological Sciences

Academic unit: Section of Molecular Biology

Description: Applications are invited for a postdoctoral position in the group of Taras Nazarko studying mechanisms of lipophagy, the selective autophagy of lipid droplets (LDs). Lipophagy is accomplished by delivery of LDs from the cytosol to the lysosome (or vacuole in yeast). As in other autophagic pathways, the core autophagic machinery forms the autophagic isolation membrane that sequesters the LD from the cytosol. However, how this autophagic membrane recognizes the LD after lipophagy induction is unknown. Also, it is not clear how lipophagy is kept in check the rest of the time. Therefore, lipophagy selectivity and regulation are the key gaps in our understanding of this pathway. A postdoctoral scholar will develop a project in one of these areas. Mechanistic understanding in these areas is critical for the precise control of lipophagy in humans for the prevention and treatment of various lipid accumulation diseases, like atherosclerosis and obesity. Initial appointment is for 1 year with possible extension for up to 5 years of overall postdoctoral training. Salary is commensurate with experience (http://postdoc.ucsd.edu/appointment-guidelines/).

Applicant requirements: The successful applicants will have a recent PhD in biochemistry, genetics, molecular or cell biology and a strong background in YEAST genetics, protein biochemistry and fluorescence microscopy. Expertise with mammalian cells or zebrafish model is a plus but not essential. Preference will be given to candidates with experience in autophagy pathway or with LDs.

How to apply: Please send your cover letter, CV and contact information of 3 references to Taras Nazarko, tnazarko@ucsd.edu