Difference between revisions of "YLR192C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004182 YLR192C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HCR1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HCR1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XII:539591..538794 | |nowrap| Chr XII:539591..538794 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004182 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YLR192C:''' Dual function protein involved in translation initiation as a substoichiometric component of eukaryotic translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA<ref name='S000060771'>Phan L, et al. (2001) A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met. EMBO J 20(11):2954-65 {{SGDpaper|S000060771}} PMID 11387228</ref><ref name='S000048910'>Valasek L, et al. (1999) The Saccharomyces cerevisiae HCR1 gene encoding a homologue of the p35 subunit of human translation initiation factor 3 (eIF3) is a high copy suppressor of a temperature-sensitive mutation in the Rpg1p subunit of yeast eIF3. J Biol Chem 274(39):27567-72 |
{{SGDpaper|S000048910}} PMID 10488093</ref> | {{SGDpaper|S000048910}} PMID 10488093</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
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| Systematic name | YLR192C |
| Gene name | HCR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:539591..538794 |
| Primary SGDID | S000004182 |
Description of YLR192C: Dual function protein involved in translation initiation as a substoichiometric component of eukaryotic translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA[1][2]
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References
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- ↑ Phan L, et al. (2001) A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met. EMBO J 20(11):2954-65 SGD PMID 11387228
- ↑ Valasek L, et al. (1999) The Saccharomyces cerevisiae HCR1 gene encoding a homologue of the p35 subunit of human translation initiation factor 3 (eIF3) is a high copy suppressor of a temperature-sensitive mutation in the Rpg1p subunit of yeast eIF3. J Biol Chem 274(39):27567-72 SGD PMID 10488093
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