Difference between revisions of "YDR135C"
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+ | === Protein Details === | ||
+ | [[Category:Topic:Protein Details]] | ||
+ | ==== Protein Function/Process ==== | ||
+ | [[Category:Topic:Protein Details:Protein Function/Process]] | ||
+ | Ycf1p was demonstrated to catalyze ATP-coupled transport of 73As(GS)3 into the vacuole. <ref name='S000041439'>Ghosh M, et al. (1999) Pathways of As(III) detoxification in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(9):5001-6 {{SGDpaper|S000041439}} PMID 10220408</ref> <ref name = 'CAset9517-2003-07-31'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9517 Barry Rosen] on 2003-07-31</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
+ | === Protein Details === | ||
+ | [[Category:Topic:Protein Details]] | ||
+ | ==== Protein Function/Process ==== | ||
+ | [[Category:Topic:Protein Details:Protein Function/Process]] | ||
+ | |||
+ | Ycf1p was demonstrated to catalyze ATP-coupled transport of 73As(GS)3 into the vacuole. <ref name='S000041439'>Ghosh M, et al. (1999) Pathways of As(III) detoxification in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(9):5001-6 {{SGDpaper|S000041439}} PMID 10220408</ref> <ref name = 'CAset9517-2003-07-31'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9517 Barry Rosen] on 2003-07-31</ref> | ||
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==References== | ==References== | ||
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Revision as of 17:05, 23 January 2007
Share your knowledge...Edit this entry!
Systematic name | YDR135C | |
Gene name | YCF1 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr IV:727548..723001 | |
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Description of YDR135C: Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR[1][2][3][4][5]
Protein Details
Protein Function/Process
Ycf1p was demonstrated to catalyze ATP-coupled transport of 73As(GS)3 into the vacuole. [6] [7]
Contents
Community Commentary
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Protein Details
Protein Function/Process
Ycf1p was demonstrated to catalyze ATP-coupled transport of 73As(GS)3 into the vacuole. [6] [7]
References
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- ↑ Gueldry O, et al. (2003) Ycf1p-dependent Hg(II) detoxification in Saccharomyces cerevisiae. Eur J Biochem 270(11):2486-96 SGD PMID 12755704
- ↑ Szczypka MS, et al. (1994) A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein. J Biol Chem 269(36):22853-7 SGD PMID 7521334
- ↑ Li ZS, et al. (1997) A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. Proc Natl Acad Sci U S A 94(1):42-7 SGD PMID 8990158
- ↑ Li ZS, et al. (1996) The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem 271(11):6509-17 SGD PMID 8626454
- ↑ Petrovic S, et al. (2000) The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 16(6):561-71 SGD PMID 10790694
- ↑ 6.0 6.1 Ghosh M, et al. (1999) Pathways of As(III) detoxification in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(9):5001-6 SGD PMID 10220408
- ↑ 7.0 7.1 submitted by Barry Rosen on 2003-07-31
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