Difference between revisions of "YKL157W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YKL157W YKL157W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001640 YKL157W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''APE2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''APE2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr XI:154996..158186
 
|nowrap| Chr XI:154996..158186
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001640
 
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'''Description of {{PAGENAME}}:''' Zinc-dependent metallopeptidase yscII, may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W<ref name='S000053939'>Garcia-Alvarez N, et al. (1991) Molecular cloning of soluble aminopeptidases from Saccharomyces cerevisiae. Sequence analysis of aminopeptidase yscII, a putative zinc-metallopeptidase. Eur J Biochem 202(3):993-1002 {{SGDpaper|S000053939}} PMID 1765107</ref><ref name='S000051861'>Hirsch HH, et al. (1988) Aminopeptidase yscII of yeast. Isolation of mutants and their biochemical and genetic analysis. Eur J Biochem 173(3):589-98 {{SGDpaper|S000051861}} PMID 3286257</ref><ref name='S000042737'>Davis CA, et al. (2000) Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast. Nucleic Acids Res 28(8):1700-6
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'''Description of YKL157W:''' Zinc-dependent metallopeptidase yscII, may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W<ref name='S000053939'>Garcia-Alvarez N, et al. (1991) Molecular cloning of soluble aminopeptidases from Saccharomyces cerevisiae. Sequence analysis of aminopeptidase yscII, a putative zinc-metallopeptidase. Eur J Biochem 202(3):993-1002 {{SGDpaper|S000053939}} PMID 1765107</ref><ref name='S000051861'>Hirsch HH, et al. (1988) Aminopeptidase yscII of yeast. Isolation of mutants and their biochemical and genetic analysis. Eur J Biochem 173(3):589-98 {{SGDpaper|S000051861}} PMID 3286257</ref><ref name='S000042737'>Davis CA, et al. (2000) Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast. Nucleic Acids Res 28(8):1700-6
 
  {{SGDpaper|S000042737}} PMID 10734188</ref>
 
  {{SGDpaper|S000042737}} PMID 10734188</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 07:46, 27 February 2007

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Systematic name YKL157W
Gene name APE2
Aliases LAP1, YKL158W
Feature type ORF, Verified
Coordinates Chr XI:154996..158186
Primary SGDID S000001640


Description of YKL157W: Zinc-dependent metallopeptidase yscII, may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W[1][2][3]




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Protein Details

Protein Localization

Protein identified in a purified mitochondrial extract. [4] [5]





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References

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  1. Garcia-Alvarez N, et al. (1991) Molecular cloning of soluble aminopeptidases from Saccharomyces cerevisiae. Sequence analysis of aminopeptidase yscII, a putative zinc-metallopeptidase. Eur J Biochem 202(3):993-1002 SGD PMID 1765107
  2. Hirsch HH, et al. (1988) Aminopeptidase yscII of yeast. Isolation of mutants and their biochemical and genetic analysis. Eur J Biochem 173(3):589-98 SGD PMID 3286257
  3. Davis CA, et al. (2000) Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast. Nucleic Acids Res 28(8):1700-6 SGD PMID 10734188
  4. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  5. submitted by Steffen Ohlmeier on 2004-04-08

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