Difference between revisions of "YGR195W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003427 YGR195W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SKI6 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SKI6 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VII:888887..889627 | |nowrap| Chr VII:888887..889627 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003427 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YGR195W:''' 3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs<ref name='S000058465'>Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 {{SGDpaper|S000058465}} PMID 9482746</ref><ref name='S000049705'>Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell 91(4):457-66 {{SGDpaper|S000049705}} PMID 9390555</ref><ref name='S000045137'>Benard L, et al. (1998) Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis. Mol Cell Biol 18(5):2688-96 |
{{SGDpaper|S000045137}} PMID 9566888</ref> | {{SGDpaper|S000045137}} PMID 9566888</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
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| Systematic name | YGR195W |
| Gene name | SKI6 |
| Aliases | ECM20, RRP41 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:888887..889627 |
| Primary SGDID | S000003427 |
Description of YGR195W: 3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs[1][2][3]
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References
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- ↑ Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 SGD PMID 9482746
- ↑ Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell 91(4):457-66 SGD PMID 9390555
- ↑ Benard L, et al. (1998) Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis. Mol Cell Biol 18(5):2688-96 SGD PMID 9566888
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