Difference between revisions of "YKL068W"
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| − | '''Description of YKL068W:''' | + | '''Description of YKL068W:''' FG-nucleoporin component of central core of the nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier and is involved in gene tethering at the nuclear periphery; homologous to Nup116p<ref name='S000145463'>Jovanovic-Talisman T, et al. (2009) Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature 457(7232):1023-7 {{SGDpaper|S000145463}} PMID 19098896</ref><ref name='S000138391'>Light WH, et al. (2010) Interaction of a DNA Zip code with the nuclear pore complex promotes H2A.Z incorporation and INO1 transcriptional memory. Mol Cell 40(1):112-25 {{SGDpaper|S000138391}} PMID 20932479</ref><ref name='S000146077'>Meinema AC, et al. (2011) Long unfolded linkers facilitate membrane protein import through the nuclear pore complex. Science 333(6038):90-3 {{SGDpaper|S000146077}} PMID 21659568</ref><ref name='S000081345'>Menon BB, et al. (2005) Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci U S A 102(16):5749-54 {{SGDpaper|S000081345}} PMID 15817685</ref><ref name='S000122438'>Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 {{SGDpaper|S000122438}} PMID 17418788</ref><ref name='S000075312'>Pyhtila B and Rexach M (2003) A gradient of affinity for the karyopherin Kap95p along the yeast nuclear pore complex. J Biol Chem 278(43):42699-709 {{SGDpaper|S000075312}} PMID 12917401</ref><ref name='S000056415'>Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 {{SGDpaper|S000056415}} PMID 10684247</ref><ref name='S000059705'>Strawn LA, et al. (2001) The GLFG regions of Nup116p and Nup100p serve as binding sites for both Kap95p and Mex67p at the nuclear pore complex. J Biol Chem 276(9):6445-52 |
{{SGDpaper|S000059705}} PMID 11104765</ref> | {{SGDpaper|S000059705}} PMID 11104765</ref> | ||
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Latest revision as of 14:05, 19 June 2012
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| Systematic name | YKL068W |
| Gene name | NUP100 |
| Aliases | NSP100, [NUP100+] |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:310199..313078 |
| Primary SGDID | S000001551 |
Description of YKL068W: FG-nucleoporin component of central core of the nuclear pore complex (NPC); contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier and is involved in gene tethering at the nuclear periphery; homologous to Nup116p[1][2][3][4][5][6][7][8]
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References
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- Jump up ↑ Jovanovic-Talisman T, et al. (2009) Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature 457(7232):1023-7 SGD PMID 19098896
- Jump up ↑ Light WH, et al. (2010) Interaction of a DNA Zip code with the nuclear pore complex promotes H2A.Z incorporation and INO1 transcriptional memory. Mol Cell 40(1):112-25 SGD PMID 20932479
- Jump up ↑ Meinema AC, et al. (2011) Long unfolded linkers facilitate membrane protein import through the nuclear pore complex. Science 333(6038):90-3 SGD PMID 21659568
- Jump up ↑ Menon BB, et al. (2005) Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci U S A 102(16):5749-54 SGD PMID 15817685
- Jump up ↑ Patel SS, et al. (2007) Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129(1):83-96 SGD PMID 17418788
- Jump up ↑ Pyhtila B and Rexach M (2003) A gradient of affinity for the karyopherin Kap95p along the yeast nuclear pore complex. J Biol Chem 278(43):42699-709 SGD PMID 12917401
- Jump up ↑ Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 SGD PMID 10684247
- Jump up ↑ Strawn LA, et al. (2001) The GLFG regions of Nup116p and Nup100p serve as binding sites for both Kap95p and Mex67p at the nuclear pore complex. J Biol Chem 276(9):6445-52 SGD PMID 11104765
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