Difference between revisions of "YER123W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000925 YER123W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YCK3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YCK3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr V:404809..406383 | |nowrap| Chr V:404809..406383 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000925 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YER123W:''' Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of the HOPS complex subunit, Vps41p; shares overlapping essential functions with Hrr25p<ref name='S000080774'>LaGrassa TJ and Ungermann C (2005) The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex. J Cell Biol 168(3):401-14 {{SGDpaper|S000080774}} PMID 15684030</ref><ref name='S000077538'>Sun B, et al. (2004) The yeast casein kinase Yck3p is palmitoylated, then sorted to the vacuolar membrane with AP-3-dependent recognition of a YXXPhi adaptin sorting signal. Mol Biol Cell 15(3):1397-406 {{SGDpaper|S000077538}} PMID 14668479</ref><ref name='S000051920'>Wang X, et al. (1996) Prenylated isoforms of yeast casein kinase I, including the novel Yck3p, suppress the gcs1 blockage of cell proliferation from stationary phase. Mol Cell Biol 16(10):5375-85 |
{{SGDpaper|S000051920}} PMID 8816449</ref> | {{SGDpaper|S000051920}} PMID 8816449</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:45, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YER123W |
| Gene name | YCK3 |
| Aliases | CKI3 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:404809..406383 |
| Primary SGDID | S000000925 |
Description of YER123W: Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of the HOPS complex subunit, Vps41p; shares overlapping essential functions with Hrr25p[1][2][3]
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References
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- ↑ LaGrassa TJ and Ungermann C (2005) The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex. J Cell Biol 168(3):401-14 SGD PMID 15684030
- ↑ Sun B, et al. (2004) The yeast casein kinase Yck3p is palmitoylated, then sorted to the vacuolar membrane with AP-3-dependent recognition of a YXXPhi adaptin sorting signal. Mol Biol Cell 15(3):1397-406 SGD PMID 14668479
- ↑ Wang X, et al. (1996) Prenylated isoforms of yeast casein kinase I, including the novel Yck3p, suppress the gcs1 blockage of cell proliferation from stationary phase. Mol Cell Biol 16(10):5375-85 SGD PMID 8816449
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