Difference between revisions of "YER068W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000870 YER068W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MOT2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MOT2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr V:293048..294811 | |nowrap| Chr V:293048..294811 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000870 | ||
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| − | '''Description of | + | '''Description of YER068W:''' Component of the CCR4-NOT complex, which has multiple roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitylates subunits of the nascent polypeptide-associated complex (NAC)<ref name='S000118045'>Panasenko O, et al. (2006) The Yeast Ccr4-Not Complex Controls Ubiquitination of the Nascent-associated Polypeptide (NAC-EGD) Complex. J Biol Chem 281(42):31389-98 {{SGDpaper|S000118045}} PMID 16926149</ref><ref name='S000074806'>Denis CL, et al. (2001) Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation. Genetics 158(2):627-34 {{SGDpaper|S000074806}} PMID 11404327</ref><ref name='S000062056'>Badarinarayana V, et al. (2000) Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. Genetics 155(3):1045-54 {{SGDpaper|S000062056}} PMID 10880468</ref><ref name='S000049134'>Liu HY, et al. (1998) The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively. EMBO J 17(4):1096-106 {{SGDpaper|S000049134}} PMID 9463387</ref><ref name='S000042122'>Bai Y, et al. (1999) The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5. Mol Cell Biol 19(10):6642-51 |
{{SGDpaper|S000042122}} PMID 10490603</ref> | {{SGDpaper|S000042122}} PMID 10490603</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Revision as of 07:45, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YER068W |
| Gene name | MOT2 |
| Aliases | NOT4, SIG1 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:293048..294811 |
| Primary SGDID | S000000870 |
Description of YER068W: Component of the CCR4-NOT complex, which has multiple roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitylates subunits of the nascent polypeptide-associated complex (NAC)[1][2][3][4][5]
</protect>
Contents
Community Commentary
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References
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- ↑ Panasenko O, et al. (2006) The Yeast Ccr4-Not Complex Controls Ubiquitination of the Nascent-associated Polypeptide (NAC-EGD) Complex. J Biol Chem 281(42):31389-98 SGD PMID 16926149
- ↑ Denis CL, et al. (2001) Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation. Genetics 158(2):627-34 SGD PMID 11404327
- ↑ Badarinarayana V, et al. (2000) Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. Genetics 155(3):1045-54 SGD PMID 10880468
- ↑ Liu HY, et al. (1998) The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively. EMBO J 17(4):1096-106 SGD PMID 9463387
- ↑ Bai Y, et al. (1999) The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5. Mol Cell Biol 19(10):6642-51 SGD PMID 10490603
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