Difference between revisions of "YDL120W"
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| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Genetic ==== | ||
| + | [[Category:Topic:Interactions:Genetic]] | ||
| + | YDL120W is suppressed by RAS2 [[Category:Genetic Interaction with RAS2]] | ||
| + | |||
| + | '''Strain Background''': W303-1B<br> | ||
| + | '''Mutation type(s)''': deletion, partial deletion | ||
| + | |||
| + | A mutation in RAS2 supressed a growth defect of deltaYFH1 strain on toxic levels of iron in growth media. <ref name='S000075657'>Kucej M and Foury F (2003) Iron toxicity protection by truncated Ras2 GTPase in yeast strain lacking frataxin. Biochem Biophys Res Commun 310(3):986-91 {{SGDpaper|S000075657}} PMID 14550302</ref> <ref name = 'CAset3226-2004-03-26'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=3226 Martin Kucej] on 2004-03-26</ref> | ||
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| + | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Genetic ==== | ||
| + | [[Category:Topic:Interactions:Genetic]] | ||
| + | YDL120W is suppressed by RAS2 [[Category:Genetic Interaction with RAS2]] | ||
| + | |||
| + | |||
| + | '''Strain Background''': W303-1B<br> | ||
| + | '''Mutation type(s)''': deletion, partial deletion | ||
| + | |||
| + | A mutation in RAS2 supressed a growth defect of deltaYFH1 strain on toxic levels of iron in growth media. <ref name='S000075657'>Kucej M and Foury F (2003) Iron toxicity protection by truncated Ras2 GTPase in yeast strain lacking frataxin. Biochem Biophys Res Commun 310(3):986-91 {{SGDpaper|S000075657}} PMID 14550302</ref> <ref name = 'CAset3226-2004-03-26'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=3226 Martin Kucej] on 2004-03-26</ref> | ||
| + | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
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{{RefHelp}} | {{RefHelp}} | ||
Revision as of 16:05, 23 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YDL120W | |
| Gene name | YFH1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr IV:245923..246447 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YDL120W: Frataxin, regulates mitochondrial iron accumulation; interacts with Isu1p which promotes Fe-S cluster assembly; interacts with electron transport chain components and may influence respiration; human homolog involved in Friedrich's ataxia[1][2][3][4]
Interactions
Genetic
YDL120W is suppressed by RAS2
Strain Background: W303-1B
Mutation type(s): deletion, partial deletion
A mutation in RAS2 supressed a growth defect of deltaYFH1 strain on toxic levels of iron in growth media. [5] [6]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Genetic
YDL120W is suppressed by RAS2
Strain Background: W303-1B
Mutation type(s): deletion, partial deletion
A mutation in RAS2 supressed a growth defect of deltaYFH1 strain on toxic levels of iron in growth media. [5] [6]
References
See Help:References on how to add references
- ↑ Gonzalez-Cabo P, et al. (2005) Frataxin interacts functionally with mitochondrial electron transport chain proteins. Hum Mol Genet 14(15):2091-8 SGD PMID 15961414
- ↑ Zhang Y, et al. (2005) Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis. J Biol Chem 280(20):19794-807 SGD PMID 15767258
- ↑ Ramazzotti A, et al. (2004) Mitochondrial functional interactions between frataxin and Isu1p, the iron-sulfur cluster scaffold protein, in Saccharomyces cerevisiae. FEBS Lett 557(1-3):215-20 SGD PMID 14741370
- ↑ Babcock M, et al. (1997) Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin. Science 276(5319):1709-12 SGD PMID 9180083
- ↑ 5.0 5.1 Kucej M and Foury F (2003) Iron toxicity protection by truncated Ras2 GTPase in yeast strain lacking frataxin. Biochem Biophys Res Commun 310(3):986-91 SGD PMID 14550302
- ↑ 6.0 6.1 submitted by Martin Kucej on 2004-03-26
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