Difference between revisions of "YDR419W"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDR419W YDR419W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002827 YDR419W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD30 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD30 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr IV:1303166..1305064
 
|nowrap| Chr IV:1303166..1305064
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002827
 
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'''Description of {{PAGENAME}}:''' DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins<ref name='S000075149'>Washington MT, et al. (2003) The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. Mol Cell Biol 23(22):8316-22 {{SGDpaper|S000075149}} PMID 14585988</ref><ref name='S000070428'>Prakash S and Prakash L (2002) Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair. Genes Dev 16(15):1872-83 {{SGDpaper|S000070428}} PMID 12154119</ref><ref name='S000051688'>Yuan F, et al. (2000) Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J Biol Chem 275(11):8233-9 {{SGDpaper|S000051688}} PMID 10713149</ref><ref name='S000046956'>Johnson RE, et al. (1999) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Science 283(5404):1001-4
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'''Description of YDR419W:''' DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins<ref name='S000075149'>Washington MT, et al. (2003) The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. Mol Cell Biol 23(22):8316-22 {{SGDpaper|S000075149}} PMID 14585988</ref><ref name='S000070428'>Prakash S and Prakash L (2002) Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair. Genes Dev 16(15):1872-83 {{SGDpaper|S000070428}} PMID 12154119</ref><ref name='S000051688'>Yuan F, et al. (2000) Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J Biol Chem 275(11):8233-9 {{SGDpaper|S000051688}} PMID 10713149</ref><ref name='S000046956'>Johnson RE, et al. (1999) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Science 283(5404):1001-4
 
  {{SGDpaper|S000046956}} PMID 9974380</ref>
 
  {{SGDpaper|S000046956}} PMID 9974380</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 07:46, 27 February 2007

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Systematic name YDR419W
Gene name RAD30
Aliases DBH1
Feature type ORF, Verified
Coordinates Chr IV:1303166..1305064
Primary SGDID S000002827


Description of YDR419W: DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins[1][2][3][4]




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References

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  1. Washington MT, et al. (2003) The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. Mol Cell Biol 23(22):8316-22 SGD PMID 14585988
  2. Prakash S and Prakash L (2002) Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair. Genes Dev 16(15):1872-83 SGD PMID 12154119
  3. Yuan F, et al. (2000) Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J Biol Chem 275(11):8233-9 SGD PMID 10713149
  4. Johnson RE, et al. (1999) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Science 283(5404):1001-4 SGD PMID 9974380

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