Difference between revisions of "YDL044C"
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| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Genetic ==== | ||
| + | [[Category:Topic:Interactions:Genetic]] | ||
| + | YDL044C is suppressed by SLS1 [[Category:Genetic Interaction with SLS1]] | ||
| + | |||
| + | '''Strain Background''': DBY2006<br> | ||
| + | '''Genotype''': ACB1<br> | ||
| + | '''Mutation type(s)''': null | ||
| + | |||
| + | The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. <ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | ==== Two Hybrid ==== | ||
| + | [[Category:Topic:Interactions:Two Hybrid]] | ||
| + | Two Hybrid interaction with RPO41 [[Category:Two Hybrid Interactions with RPO41]]<br> | ||
| + | The mitochondrial matrix protein Mtf2p/Nam1p interacts with the amino-terminal domain of mtRNA polymerase (Rpo41p) to couple post-transcriptional events to transcription during mitochondrial gene expression. <ref name='S000060339'>Rodeheffer MS, et al. (2001) Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase. J Biol Chem 276(11):8616-22 {{SGDpaper|S000060339}} PMID 11118450</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Genetic ==== | ||
| + | [[Category:Topic:Interactions:Genetic]] | ||
| + | YDL044C is suppressed by SLS1 [[Category:Genetic Interaction with SLS1]] | ||
| + | |||
| + | |||
| + | '''Strain Background''': DBY2006<br> | ||
| + | '''Genotype''': ACB1<br> | ||
| + | '''Mutation type(s)''': null | ||
| + | |||
| + | The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. <ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | ==== Two Hybrid ==== | ||
| + | [[Category:Topic:Interactions:Two Hybrid]] | ||
| + | Two Hybrid interaction with RPO41 [[Category:Two Hybrid Interactions with RPO41]]<br> | ||
| + | The mitochondrial matrix protein Mtf2p/Nam1p interacts with the amino-terminal domain of mtRNA polymerase (Rpo41p) to couple post-transcriptional events to transcription during mitochondrial gene expression. <ref name='S000060339'>Rodeheffer MS, et al. (2001) Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase. J Biol Chem 276(11):8616-22 {{SGDpaper|S000060339}} PMID 11118450</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref> | ||
| + | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
Revision as of 16:05, 23 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YDL044C | |
| Gene name | MTF2 | |
| Aliases | NAM1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr IV:375286..373964 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YDL044C: Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription[1][2][3]
Interactions
Genetic
YDL044C is suppressed by SLS1
Strain Background: DBY2006
Genotype: ACB1
Mutation type(s): null
The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. [4] [5]
Two Hybrid
Two Hybrid interaction with RPO41
The mitochondrial matrix protein Mtf2p/Nam1p interacts with the amino-terminal domain of mtRNA polymerase (Rpo41p) to couple post-transcriptional events to transcription during mitochondrial gene expression. [1] [5]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Genetic
YDL044C is suppressed by SLS1
Strain Background: DBY2006
Genotype: ACB1
Mutation type(s): null
The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. [4] [5]
Two Hybrid
Two Hybrid interaction with RPO41
The mitochondrial matrix protein Mtf2p/Nam1p interacts with the amino-terminal domain of mtRNA polymerase (Rpo41p) to couple post-transcriptional events to transcription during mitochondrial gene expression. [1] [5]
References
See Help:References on how to add references
- ↑ 1.0 1.1 1.2 Rodeheffer MS, et al. (2001) Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase. J Biol Chem 276(11):8616-22 SGD PMID 11118450
- ↑ Asher EB, et al. (1989) Novel class of nuclear genes involved in both mRNA splicing and protein synthesis in Saccharomyces cerevisiae mitochondria. Mol Gen Genet 215(3):517-28 SGD PMID 2651895
- ↑ Wallis MG, et al. (1994) The NAM1 protein (NAM1p), which is selectively required for cox1, cytb and atp6 transcript processing/stabilisation, is located in the yeast mitochondrial matrix. Eur J Biochem 222(1):27-32 SGD PMID 8200349
- ↑ 4.0 4.1 Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 SGD PMID 11805046
- ↑ 5.0 5.1 5.2 5.3 submitted by Gerald Shadel on 2003-06-05
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