Difference between revisions of "YMR246W"
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| − | '''Description of YMR246W:''' Long chain fatty acyl-CoA synthetase | + | '''Description of YMR246W:''' Long chain fatty acyl-CoA synthetase; activates imported fatty acids with a preference for C12:0-C16:0 chain lengths; functions in long chain fatty acid import; important for survival during stationary phase; localized to lipid particles; involved in sphingolipid-to-glycerolipid metabolism<ref name='S000049471'>Ashrafi K, et al. (1998) A role for Saccharomyces cerevisiae fatty acid activation protein 4 in regulating protein N-myristoylation during entry into stationary phase. J Biol Chem 273(40):25864-74 {{SGDpaper|S000049471}} PMID 9748261</ref><ref name='S000048561'>Athenstaedt K, et al. (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8 {{SGDpaper|S000048561}} PMID 10515935</ref><ref name='S000039598'>Johnson DR, et al. (1994) Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N-myristoylation and cellular lipid metabolism. J Cell Biol 127(3):751-62 {{SGDpaper|S000039598}} PMID 7962057</ref><ref name='S000149644'>Nakahara K, et al. (2012) The sjogren-larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway. Mol Cell 46(4):461-71 {{SGDpaper|S000149644}} PMID 22633490</ref><ref name='S000073135'>Zou Z, et al. (2003) Vectorial acylation in Saccharomyces cerevisiae. Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex. J Biol Chem 278(18):16414-22 |
{{SGDpaper|S000073135}} PMID 12601005</ref> | {{SGDpaper|S000073135}} PMID 12601005</ref> | ||
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Latest revision as of 13:05, 5 June 2012
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| Systematic name | YMR246W |
| Gene name | FAA4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:759807..761891 |
| Primary SGDID | S000004860 |
Description of YMR246W: Long chain fatty acyl-CoA synthetase; activates imported fatty acids with a preference for C12:0-C16:0 chain lengths; functions in long chain fatty acid import; important for survival during stationary phase; localized to lipid particles; involved in sphingolipid-to-glycerolipid metabolism[1][2][3][4][5]
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References
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- ↑ Ashrafi K, et al. (1998) A role for Saccharomyces cerevisiae fatty acid activation protein 4 in regulating protein N-myristoylation during entry into stationary phase. J Biol Chem 273(40):25864-74 SGD PMID 9748261
- ↑ Athenstaedt K, et al. (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8 SGD PMID 10515935
- ↑ Johnson DR, et al. (1994) Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N-myristoylation and cellular lipid metabolism. J Cell Biol 127(3):751-62 SGD PMID 7962057
- ↑ Nakahara K, et al. (2012) The sjogren-larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway. Mol Cell 46(4):461-71 SGD PMID 22633490
- ↑ Zou Z, et al. (2003) Vectorial acylation in Saccharomyces cerevisiae. Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex. J Biol Chem 278(18):16414-22 SGD PMID 12601005
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