Difference between revisions of "YDR098C"

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'''Description of YDR098C:''' Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage<ref name='S000048888'>Rodriguez-Manzaneque MT, et al. (1999) Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae. Mol Cell Biol 19(12):8180-90
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'''Description of YDR098C:''' Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage; evidence exists indicating that the translation start site is not Met1 as currently annotated, but rather Met36<ref name='S000150024'>Dingra NN (2005) Characterization of the Role of Glutaredoxin 3 and its Binding Partners in Maintaining Iron Homeostasis in Saccharomyces cerevisiae  () {{SGDpaper|S000150024}} PMID </ref><ref name='S000131452'>Li H, et al. (2009) The yeast iron regulatory proteins Grx3/4 and Fra2 form heterodimeric complexes containing a [2Fe-2S] cluster with cysteinyl and histidyl ligation. Biochemistry 48(40):9569-81 {{SGDpaper|S000131452}} PMID 19715344</ref><ref name='S000048888'>Rodriguez-Manzaneque MT, et al. (1999) Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae. Mol Cell Biol 19(12):8180-90
 
  {{SGDpaper|S000048888}} PMID 10567543</ref>
 
  {{SGDpaper|S000048888}} PMID 10567543</ref>
 
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Latest revision as of 14:05, 9 July 2012

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Systematic name YDR098C
Gene name GRX3
Aliases
Feature type ORF, Verified
Coordinates Chr IV:645035..644178
Primary SGDID S000002505


Description of YDR098C: Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage; evidence exists indicating that the translation start site is not Met1 as currently annotated, but rather Met36[1][2][3]




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References

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  1. Dingra NN (2005) Characterization of the Role of Glutaredoxin 3 and its Binding Partners in Maintaining Iron Homeostasis in Saccharomyces cerevisiae () SGD PMID
  2. Li H, et al. (2009) The yeast iron regulatory proteins Grx3/4 and Fra2 form heterodimeric complexes containing a [2Fe-2S] cluster with cysteinyl and histidyl ligation. Biochemistry 48(40):9569-81 SGD PMID 19715344
  3. Rodriguez-Manzaneque MT, et al. (1999) Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae. Mol Cell Biol 19(12):8180-90 SGD PMID 10567543

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