Difference between revisions of "YBR061C"
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− | '''Description of YBR061C:''' 2'-O-ribose methyltransferase | + | '''Description of YBR061C:''' 2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of the tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively<ref name='S000150587'>Guy MP, et al. (2012) Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop. RNA () {{SGDpaper|S000150587}} PMID 22912484</ref><ref name='S000069485'>Pintard L, et al. (2002) Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop. EMBO J 21(7):1811-20 |
{{SGDpaper|S000069485}} PMID 11927565</ref> | {{SGDpaper|S000069485}} PMID 11927565</ref> | ||
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Latest revision as of 14:05, 10 September 2012
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Systematic name | YBR061C |
Gene name | TRM7 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr II:365719..364787 |
Primary SGDID | S000000265 |
Description of YBR061C: 2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of the tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively[1][2]
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References
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- ↑ Guy MP, et al. (2012) Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop. RNA () SGD PMID 22912484
- ↑ Pintard L, et al. (2002) Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop. EMBO J 21(7):1811-20 SGD PMID 11927565
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