Difference between revisions of "YNL138W"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 13:02, 21 February 2007
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| Systematic name | YNL138W |
| Gene name | SRV2 |
| Aliases | CAP |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:366743..368323 |
Description of YNL138W: CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis[1][2][3]
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References
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- ↑ Mattila PK, et al. (2004) A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein. Mol Biol Cell 15(11):5158-71 SGD PMID 15356265
- ↑ Fedor-Chaiken M, et al. (1990) SRV2, a gene required for RAS activation of adenylate cyclase in yeast. Cell 61(2):329-40 SGD PMID 2158860
- ↑ Freeman NL, et al. (1995) An actin monomer binding activity localizes to the carboxyl-terminal half of the Saccharomyces cerevisiae cyclase-associated protein. J Biol Chem 270(10):5680-5 SGD PMID 7890691
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