Difference between revisions of "YLR035C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
(Automated import of articles)
Line 16: Line 16:
 
|}
 
|}
 
<br>
 
<br>
'''Description of {{PAGENAME}}:''' Protein required for DNA mismatch repair in mitosis and meiosis; involved in the repair of mutational intermediates; forms a complex with Pms1p and Msh1p to repair mismatched DNA<ref name='S000057873'>Kolodner R (1996) Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev 10(12):1433-42 {{SGDpaper|S000057873}} PMID 8666228</ref><ref name='S000042567'>Harfe BD, et al. (2000) Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10(3):145-8
+
'''Description of {{PAGENAME}}:''' Protein required for DNA mismatch repair in mitosis; involved in the repair of mutational intermediates; forms a complex with Pms1p and Msh1p to repair mismatched DNA<ref name='S000057873'>Kolodner R (1996) Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev 10(12):1433-42 {{SGDpaper|S000057873}} PMID 8666228</ref><ref name='S000042567'>Harfe BD, et al. (2000) Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10(3):145-8
 
  {{SGDpaper|S000042567}} PMID 10679328</ref>
 
  {{SGDpaper|S000042567}} PMID 10679328</ref>
 
<br>
 
<br>
Line 36: Line 36:
  
 
{{ShortCenteredHR}}
 
{{ShortCenteredHR}}
 +
 +
 +
 +
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 +
<!--
 +
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 +
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 +
J Biol Chem 278(5):3265-74</ref>
 +
-->
  
 
<protect>
 
<protect>

Revision as of 12:02, 21 February 2007

Share your knowledge...Edit this entry! <protect>

Systematic name YLR035C
Gene name MLH2
Aliases
Feature type ORF, Verified
Coordinates Chr XII:214457..212370


Description of YLR035C: Protein required for DNA mismatch repair in mitosis; involved in the repair of mutational intermediates; forms a complex with Pms1p and Msh1p to repair mismatched DNA[1][2]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]




<protect>

References

See Help:References on how to add references

  1. Kolodner R (1996) Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev 10(12):1433-42 SGD PMID 8666228
  2. Harfe BD, et al. (2000) Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10(3):145-8 SGD PMID 10679328
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-29

See Help:Categories on how to add the wiki page for this gene to a Category </protect>