Difference between revisions of "YJL104W"
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| − | '''Description of {{PAGENAME}}:''' Constituent of the mitochondrial import motor associated with the presequence translocase, along with Ssc1p, Tim44p, Mge1p, and Pam18p; | + | '''Description of {{PAGENAME}}:''' Constituent of the mitochondrial import motor associated with the presequence translocase, along with Ssc1p, Tim44p, Mge1p, and Pam18p; forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains J-like domain<ref name='S000120441'>Mokranjac D, et al. (2006) Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor. EMBO J 25(19):4675-85 {{SGDpaper|S000120441}} PMID 16977310</ref><ref name='S000075546'>Kozany C, et al. (2004) The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase. Nat Struct Mol Biol 11(3):234-41 {{SGDpaper|S000075546}} PMID 14981506</ref><ref name='S000075545'>Frazier AE, et al. (2004) Pam16 has an essential role in the mitochondrial protein import motor. Nat Struct Mol Biol 11(3):226-33 |
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 12:02, 21 February 2007
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| Systematic name | YJL104W |
| Gene name | PAM16 |
| Aliases | MIA1, TIM16 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:227323..227772 |
Description of YJL104W: Constituent of the mitochondrial import motor associated with the presequence translocase, along with Ssc1p, Tim44p, Mge1p, and Pam18p; forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains J-like domain[1][2][3]
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Community Commentary
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Protein Details
Protein Localization
Protein identified in a purified mitochondrial extract. [4] [5]
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References
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- ↑ Mokranjac D, et al. (2006) Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor. EMBO J 25(19):4675-85 SGD PMID 16977310
- ↑ Kozany C, et al. (2004) The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase. Nat Struct Mol Biol 11(3):234-41 SGD PMID 14981506
- ↑ Frazier AE, et al. (2004) Pam16 has an essential role in the mitochondrial protein import motor. Nat Struct Mol Biol 11(3):226-33 SGD PMID 14981507
- ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- ↑ submitted by Steffen Ohlmeier on 2004-04-08
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