Difference between revisions of "YOL027C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005387 YOL027C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MDM38 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MDM38 '' |
Latest revision as of 07:45, 23 January 2012
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Systematic name | YOL027C |
Gene name | MDM38 |
Aliases | MKH1 |
Feature type | ORF, Verified |
Coordinates | Chr XV:273724..272003 |
Primary SGDID | S000005387 |
Description of YOL027C: Mitochondrial protein, forms a complex with Mba1p to facilitate recruitment of mRNA-specific translational activators to ribosomes; roles in protein export and K+/H+ exchange; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome[1][2][3][4][5]
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Contents
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References
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- ↑ Bauerschmitt H, et al. (2010) Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation. Mol Biol Cell 21(12):1937-44 SGD PMID 20427570
- ↑ Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 SGD PMID 11907266
- ↑ Frazier AE, et al. (2006) Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. J Cell Biol 172(4):553-64 SGD PMID 16476776
- ↑ Froschauer E, et al. (2005) Electroneutral K+/H+ exchange in mitochondrial membrane vesicles involves Yol027/Letm1 proteins. Biochim Biophys Acta 1711(1):41-8 SGD PMID 15904662
- ↑ Nowikovsky K, et al. (2004) The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome. J Biol Chem 279(29):30307-15 SGD PMID 15138253
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