Difference between revisions of "YHR133C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YHR133C
Gene name NSG1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:371600..370725


Description of YHR133C: Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins[1]




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References

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  1. Flury I, et al. (2005) INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins. EMBO J 24(22):3917-26 SGD PMID 16270032

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