Difference between revisions of "YHR099W"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 12:02, 21 February 2007
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| Systematic name | YHR099W |
| Gene name | TRA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:302764..313998 |
Description of YHR099W: Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation[1][2][3][4]
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References
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- ↑ Bhaumik SR, et al. (2004) In vivo target of a transcriptional activator revealed by fluorescence resonance energy transfer. Genes Dev 18(3):333-43 SGD PMID 14871930
- ↑ Brown CE, et al. (2001) Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit. Science 292(5525):2333-7 SGD PMID 11423663
- ↑ Saleh A, et al. (1998) Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes. J Biol Chem 273(41):26559-65 SGD PMID 9756893
- ↑ Grant PA, et al. (1998) The ATM-related cofactor Tra1 is a component of the purified SAGA complex. Mol Cell 2(6):863-7 SGD PMID 9885573
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