Difference between revisions of "YHR068W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 12:02, 21 February 2007

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Systematic name YHR068W
Gene name DYS1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:232135..233298


Description of YHR068W: Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric[1][2][3]




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References

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  1. Thompson GM, et al. (2003) Mapping eIF5A binding sites for Dys1 and Lia1: in vivo evidence for regulation of eIF5A hypusination. FEBS Lett 555(3):464-8 SGD PMID 14675757
  2. Abid R, et al. (1997) Novel features of the functional site and expression of the yeast deoxyhypusine synthase. Biol Signals 6(3):157-65 SGD PMID 9285099
  3. Kang KR, et al. (1995) Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase. Expression and characterization of the enzyme. J Biol Chem 270(31):18408-12 SGD PMID 7629166

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