Difference between revisions of "YPL006W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005927 YPL006W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005927 YPL006W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NCR1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''NCR1 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YPL006W
Gene name NCR1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:544631..548143
Primary SGDID S000005927


Description of YPL006W: Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein[1][2]




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References

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  1. Malathi K, et al. (2004) Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution. J Cell Biol 164(4):547-56 SGD PMID 14970192
  2. Zhang S, et al. (2004) Ncr1p, the yeast ortholog of mammalian Niemann Pick C1 protein, is dispensable for endocytic transport. Traffic 5(12):1017-30 SGD PMID 15522102

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