Difference between revisions of "YGL021W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YGL021W
Gene name ALK1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:454790..457072


Description of YGL021W: Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins[1][2][3]




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References

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  1. Nespoli A, et al. (2006) Alk1 and Alk2 are Two New Cell Cycle-Regulated Haspin-Like Proteins in Budding Yeast. Cell Cycle 5(13):1464-71 SGD PMID 16855400
  2. Higgins JM (2003) Structure, function and evolution of haspin and haspin-related proteins, a distinctive group of eukaryotic protein kinases. Cell Mol Life Sci 60(3):446-62 SGD PMID 12737306
  3. Chen WN, et al. (1991) The YGL021 gene encodes a putative membrane protein with a putative leucine zipper motif. Yeast 7(3):301-3 SGD PMID 1882554

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