Difference between revisions of "YJR144W"
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| − | '''Description of YJR144W:''' Protein | + | '''Description of YJR144W:''' Protein with a role in mitochondrial DNA recombinational repair; binds to and catalyzes the annealing of single-stranded mtDNA; oligomerizes to form rings and filaments; related to Rad52-type recombination proteins, with limited overall similarity but sharing conserved functionally important residues; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage<ref name='S000049283'>Chen XJ, et al. (1993) MGM101, a nuclear gene involved in maintenance of the mitochondrial genome in Saccharomyces cerevisiae. Nucleic Acids Res 21(15):3473-7 {{SGDpaper|S000049283}} PMID 8346025</ref><ref name='S000147213'>Mbantenkhu M, et al. (2011) Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination. J Biol Chem () {{SGDpaper|S000147213}} PMID 22027892</ref><ref name='S000047653'>Meeusen S, et al. (1999) Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA. J Cell Biol 145(2):291-304 {{SGDpaper|S000047653}} PMID 10209025</ref><ref name='S000120878'>Zuo X, et al. (2007) A functional core of the mitochondrial genome maintenance protein Mgm101p in Saccharomyces cerevisiae determined with a temperature-conditional allele. FEMS Yeast Res 7(1):131-40 |
| − | {{SGDpaper| | + | {{SGDpaper|S000120878}} PMID 17311591</ref> |
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Revision as of 13:05, 10 November 2011
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| Systematic name | YJR144W |
| Gene name | MGM101 |
| Aliases | MGM9 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:700882..701691 |
| Primary SGDID | S000003905 |
Description of YJR144W: Protein with a role in mitochondrial DNA recombinational repair; binds to and catalyzes the annealing of single-stranded mtDNA; oligomerizes to form rings and filaments; related to Rad52-type recombination proteins, with limited overall similarity but sharing conserved functionally important residues; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage[1][2][3][4]
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References
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- ↑ Chen XJ, et al. (1993) MGM101, a nuclear gene involved in maintenance of the mitochondrial genome in Saccharomyces cerevisiae. Nucleic Acids Res 21(15):3473-7 SGD PMID 8346025
- ↑ Mbantenkhu M, et al. (2011) Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination. J Biol Chem () SGD PMID 22027892
- ↑ Meeusen S, et al. (1999) Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA. J Cell Biol 145(2):291-304 SGD PMID 10209025
- ↑ Zuo X, et al. (2007) A functional core of the mitochondrial genome maintenance protein Mgm101p in Saccharomyces cerevisiae determined with a temperature-conditional allele. FEMS Yeast Res 7(1):131-40 SGD PMID 17311591
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