Difference between revisions of "YGL179C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003147 YGL179C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TOS3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TOS3 '' |
Latest revision as of 06:45, 23 January 2012
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Systematic name | YGL179C |
Gene name | TOS3 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VII:165091..163409 |
Primary SGDID | S000003147 |
Description of YGL179C: Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome[1][2][3][4][5]
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Contents
Community Commentary
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References
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- ↑ Elbing K, et al. (2006) Purification and characterization of the three Snf1-activating kinases of Saccharomyces cerevisiae. Biochem J 393(Pt 3):797-805 SGD PMID 16201971
- ↑ Hedbacker K, et al. (2004) Pak1 protein kinase regulates activation and nuclear localization of Snf1-Gal83 protein kinase. Mol Cell Biol 24(18):8255-63 SGD PMID 15340085
- ↑ Hong SP, et al. (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc Natl Acad Sci U S A 100(15):8839-43 SGD PMID 12847291
- ↑ Nath N, et al. (2003) Yeast Pak1 kinase associates with and activates Snf1. Mol Cell Biol 23(11):3909-17 SGD PMID 12748292
- ↑ Sutherland CM, et al. (2003) Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex. Curr Biol 13(15):1299-305 SGD PMID 12906789
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