Difference between revisions of "YDR493W"
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| − | '''Description of YDR493W:''' | + | '''Description of YDR493W:''' Protein required for assembly of the cytochrome bc(1) complex; facilitates insertion of Rip1p into the complex at a late stage of assembly; localized to the mitochondrial matrix; null mutant exhibits a respiratory growth defect and reduced mitochondrial zinc levels, which is characteristic of mutations affecting bc(1) complex assembly; conserved in metazoans<ref name='S000133883'>Atkinson A, et al. (2010) Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function. J Biol Chem 285(25):19450-9 {{SGDpaper|S000133883}} PMID 20404342</ref><ref name='S000146271'>Atkinson A, et al. (2011) The LYR protein Mzm1 functions in the insertion of the Rieske Fe/S protein in yeast mitochondria. Mol Cell Biol () |
| − | {{SGDpaper| | + | {{SGDpaper|S000146271}} PMID 21807901</ref> |
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Revision as of 13:05, 2 December 2011
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| Systematic name | YDR493W |
| Gene name | MZM1 |
| Aliases | AIM8, FMP36 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1436217..1436588 |
| Primary SGDID | S000002901 |
Description of YDR493W: Protein required for assembly of the cytochrome bc(1) complex; facilitates insertion of Rip1p into the complex at a late stage of assembly; localized to the mitochondrial matrix; null mutant exhibits a respiratory growth defect and reduced mitochondrial zinc levels, which is characteristic of mutations affecting bc(1) complex assembly; conserved in metazoans[1][2]
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References
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- ↑ Atkinson A, et al. (2010) Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function. J Biol Chem 285(25):19450-9 SGD PMID 20404342
- ↑ Atkinson A, et al. (2011) The LYR protein Mzm1 functions in the insertion of the Rieske Fe/S protein in yeast mitochondria. Mol Cell Biol () SGD PMID 21807901
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