Difference between revisions of "YDR014W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002421 YDR014W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002421 YDR014W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD61 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD61 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YDR014W
Gene name RAD61
Aliases WPL1
Feature type ORF, Verified
Coordinates Chr IV:474046..475989
Primary SGDID S000002421


Description of YDR014W: Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin[1][2][3][4]




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References

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  1. Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127(5):955-67 SGD PMID 17113138
  2. Rolef Ben-Shahar T, et al. (2008) Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321(5888):563-6 SGD PMID 18653893
  3. Rowland BD, et al. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell 33(6):763-74 SGD PMID 19328069
  4. Sutani T, et al. (2009) Budding yeast Wpl1(Rad61)-Pds5 complex counteracts sister chromatid cohesion-establishing reaction. Curr Biol 19(6):492-7 SGD PMID 19268589

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