Difference between revisions of "YKL216W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001699 YKL216W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001699 YKL216W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''URA1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''URA1 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YKL216W
Gene name URA1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:25215..26159
Primary SGDID S000001699


Description of YKL216W: Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid[1][2][3]




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Community Commentary

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Other

Gene Origin

Horizontally transferred from lactic acid bacteria [4] [5]





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References

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  1. Guerry-Kopecko P and Wickner RB (1980) Cloning of the URA1 gene of Saccharomyces cerevisiae. J Bacteriol 143(3):1530-3 SGD PMID 6251032
  2. Lacroute F (1968) Regulation of pyrimidine biosynthesis in Saccharomyces cerevisiae. J Bacteriol 95(3):824-32 SGD PMID 5651325
  3. Vorisek J, et al. (2002) Enzymatic activities of Ura2 and Ura1 proteins (aspartate carbamoyltransferase and dihydro-orotate dehydrogenase) are present in both isolated membranes and cytoplasm of Saccharomyces cerevisiae. Yeast 19(5):449-57 SGD PMID 11921093
  4. Hall C, et al. (2005) Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryot Cell 4(6):1102-15 SGD PMID 15947202
  5. submitted by Charles Hall on 2006-06-09

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