Difference between revisions of "YIL035C"
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| − | '''Description of YIL035C:''' Alpha catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; | + | '''Description of YIL035C:''' Alpha catalytic subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases<ref name='S000069123'>Ackermann K, et al. (2001) Genes targeted by protein kinase CK2: a genome-wide expression array analysis in yeast. Mol Cell Biochem 227(1-2):59-66 {{SGDpaper|S000069123}} PMID 11827175</ref><ref name='S000071504'>Ahmed K, et al. (2002) Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol 12(5):226-30 {{SGDpaper|S000071504}} PMID 12062170</ref><ref name='S000045325'>Chen-Wu JL, et al. (1988) Isolation, sequencing, and disruption of the CKA1 gene encoding the alpha subunit of yeast casein kinase II. Mol Cell Biol 8(11):4981-90 {{SGDpaper|S000045325}} PMID 3062376</ref><ref name='S000062274'>Marin O, et al. (1999) Tyrosine versus serine/threonine phosphorylation by protein kinase casein kinase-2. A study with peptide substrates derived from immunophilin Fpr3. J Biol Chem 274(41):29260-5 |
{{SGDpaper|S000062274}} PMID 10506183</ref> | {{SGDpaper|S000062274}} PMID 10506183</ref> | ||
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Revision as of 13:05, 6 April 2011
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| Systematic name | YIL035C |
| Gene name | CKA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:288908..287790 |
| Primary SGDID | S000001297 |
Description of YIL035C: Alpha catalytic subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases[1][2][3][4]
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References
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- ↑ Ackermann K, et al. (2001) Genes targeted by protein kinase CK2: a genome-wide expression array analysis in yeast. Mol Cell Biochem 227(1-2):59-66 SGD PMID 11827175
- ↑ Ahmed K, et al. (2002) Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol 12(5):226-30 SGD PMID 12062170
- ↑ Chen-Wu JL, et al. (1988) Isolation, sequencing, and disruption of the CKA1 gene encoding the alpha subunit of yeast casein kinase II. Mol Cell Biol 8(11):4981-90 SGD PMID 3062376
- ↑ Marin O, et al. (1999) Tyrosine versus serine/threonine phosphorylation by protein kinase casein kinase-2. A study with peptide substrates derived from immunophilin Fpr3. J Biol Chem 274(41):29260-5 SGD PMID 10506183
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