Difference between revisions of "YLR205C"
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| − | '''Description of YLR205C:''' ER localized heme oxygenase, involved in | + | '''Description of YLR205C:''' ER localized heme oxygenase, involved in heme degradation during iron starvation and in the oxidative stress response; expression is regulated by AFT1 and oxidative stress; relocates to the perinuclear region in the presence of oxidants<ref name='S000073085'>Auclair K, et al. (2003) Cloning and expression of a heme binding protein from the genome of Saccharomyces cerevisiae. Protein Expr Purif 28(2):340-9 {{SGDpaper|S000073085}} PMID 12699699</ref><ref name='S000140783'>Collinson EJ, et al. (2010) The yeast homolog of heme oxygenase-1 affords cellular antioxidant protection via the transcriptional regulation of known antioxidant genes. J Biol Chem () {{SGDpaper|S000140783}} PMID 21081499</ref><ref name='S000060699'>Foury F and Talibi D (2001) Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. J Biol Chem 276(11):7762-8 {{SGDpaper|S000060699}} PMID 11112771</ref><ref name='S000119917'>Kim D, et al. (2006) Fungal heme oxygenases: Functional expression and characterization of Hmx1 from Saccharomyces cerevisiae and CaHmx1 from Candida albicans. Biochemistry 45(49):14772-80 {{SGDpaper|S000119917}} PMID 17144670</ref><ref name='S000074012'>Protchenko O and Philpott CC (2003) Regulation of intracellular heme levels by HMX1, a homologue of heme oxygenase, in Saccharomyces cerevisiae. J Biol Chem 278(38):36582-7 |
{{SGDpaper|S000074012}} PMID 12840010</ref> | {{SGDpaper|S000074012}} PMID 12840010</ref> | ||
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Revision as of 13:05, 22 November 2010
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| Systematic name | YLR205C |
| Gene name | HMX1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:553679..552726 |
| Primary SGDID | S000004195 |
Description of YLR205C: ER localized heme oxygenase, involved in heme degradation during iron starvation and in the oxidative stress response; expression is regulated by AFT1 and oxidative stress; relocates to the perinuclear region in the presence of oxidants[1][2][3][4][5]
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References
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- ↑ Auclair K, et al. (2003) Cloning and expression of a heme binding protein from the genome of Saccharomyces cerevisiae. Protein Expr Purif 28(2):340-9 SGD PMID 12699699
- ↑ Collinson EJ, et al. (2010) The yeast homolog of heme oxygenase-1 affords cellular antioxidant protection via the transcriptional regulation of known antioxidant genes. J Biol Chem () SGD PMID 21081499
- ↑ Foury F and Talibi D (2001) Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. J Biol Chem 276(11):7762-8 SGD PMID 11112771
- ↑ Kim D, et al. (2006) Fungal heme oxygenases: Functional expression and characterization of Hmx1 from Saccharomyces cerevisiae and CaHmx1 from Candida albicans. Biochemistry 45(49):14772-80 SGD PMID 17144670
- ↑ Protchenko O and Philpott CC (2003) Regulation of intracellular heme levels by HMX1, a homologue of heme oxygenase, in Saccharomyces cerevisiae. J Biol Chem 278(38):36582-7 SGD PMID 12840010
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