Difference between revisions of "YAL034W-A"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
Line 69: | Line 69: | ||
{{ShortCenteredHR}} | {{ShortCenteredHR}} | ||
+ | |||
+ | |||
+ | |||
+ | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
+ | <!-- | ||
+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
+ | --> | ||
<protect> | <protect> |
Revision as of 13:02, 21 February 2007
Share your knowledge...Edit this entry! <protect>
Systematic name | YAL034W-A |
Gene name | MTW1 |
Aliases | DSN3, NSL2 |
Feature type | ORF, Verified |
Coordinates | Chr I:79719..80588 |
Description of YAL034W-A: Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly[1]
</protect>
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Alleles, Strains, and Phenotypes
Point Mutation
Allele: mtw1-1
Strain Background: W303
Phenotype(s): Temperature(Heat) Sensitive
mtw1-1 mutants activate the spindle checkpoint in an IPL1 dependent manner. [2] [3]
Allele: mtw1-1
Strain Background: W303
Phenotype(s): Temperature(Heat) Sensitive
mtw1-1 mutants have unattached chromosomes. [2] [3]
Interactions
Genetic
YAL034W-A is suppressed by DSN1
Strain Background: W303
DSN1 is a high copy suppressor of the mtw1-1 mutant. [2] [3]
Physical
Physical interaction with CSE4
Cse4p co-immunoprecipitates with Mtw1p. [2] [3]
Physical interaction with DSN1
Mtw1p co-immunoprecipitates Dsn1p. [2] [3]
<protect>
References
See Help:References on how to add references
- ↑ De Wulf P, et al. (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17(23):2902-21 SGD PMID 14633972
- ↑ 2.0 2.1 2.2 2.3 2.4 Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 SGD PMID 14602074
- ↑ 3.0 3.1 3.2 3.3 3.4 submitted by Benjamin Pinsky on 2004-03-04
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
- ORF
- ORF, Verified
- Topic:Alleles, Strains, and Phenotypes
- Topic:Alleles, Strains, and Phenotypes:Point Mutation
- Phenotype:Temperature(Heat) Sensitive
- Topic:Interactions
- Topic:Interactions:Genetic
- Genetic Interaction with DSN1
- Topic:Interactions:Physical
- Physical Interactions with CSE4
- Physical Interactions with DSN1