Difference between revisions of "YHR100C"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr VIII: | + | |nowrap| Chr VIII:314673..314116 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001142 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001142 |
Revision as of 13:05, 3 February 2011
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Systematic name | YHR100C |
Gene name | GEP4 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VIII:314673..314116 |
Primary SGDID | S000001142 |
Description of YHR100C: Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase), dephosphorylates phosphatidylglycerolphosphate to generate phosphatidylglycerol, an essential step during cardiolipin biosynthesis; null mutant is sensitive to tunicamycin, DTT[1][2]
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References
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- ↑ Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 SGD PMID 19221197
- ↑ Osman C, et al. (2010) A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4. EMBO J 29(12):1976-87 SGD PMID 20485265
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