Difference between revisions of "YOR259C"
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− | '''Description of YOR259C:''' One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in | + | '''Description of YOR259C:''' One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in degradation of ubiquitinated substrates; contributes preferentially to ERAD; required for spindle pole body duplication; mainly nuclear localization<ref name='S000044396'>Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62 {{SGDpaper|S000044396}} PMID 9584156</ref><ref name='S000136123'>Lipson C, et al. (2008) A proteasomal ATPase contributes to dislocation of endoplasmic reticulum-associated degradation (ERAD) substrates. J Biol Chem 283(11):7166-75 {{SGDpaper|S000136123}} PMID 18174173</ref><ref name='S000044886'>McDonald HB and Byers B (1997) A proteasome cap subunit required for spindle pole body duplication in yeast. J Cell Biol 137(3):539-53 {{SGDpaper|S000044886}} PMID 9151663</ref><ref name='S000065027'>Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 {{SGDpaper|S000065027}} PMID 9724628</ref><ref name='S000047509'>Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 |
{{SGDpaper|S000047509}} PMID 10419517</ref> | {{SGDpaper|S000047509}} PMID 10419517</ref> | ||
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Revision as of 14:05, 13 September 2010
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Systematic name | YOR259C |
Gene name | RPT4 |
Aliases | CRL13, PCS1, SUG2 |
Feature type | ORF, Verified |
Coordinates | Chr XV:813708..812395 |
Primary SGDID | S000005785 |
Description of YOR259C: One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in degradation of ubiquitinated substrates; contributes preferentially to ERAD; required for spindle pole body duplication; mainly nuclear localization[1][2][3][4][5]
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References
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- ↑ Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62 SGD PMID 9584156
- ↑ Lipson C, et al. (2008) A proteasomal ATPase contributes to dislocation of endoplasmic reticulum-associated degradation (ERAD) substrates. J Biol Chem 283(11):7166-75 SGD PMID 18174173
- ↑ McDonald HB and Byers B (1997) A proteasome cap subunit required for spindle pole body duplication in yeast. J Cell Biol 137(3):539-53 SGD PMID 9151663
- ↑ Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 SGD PMID 9724628
- ↑ Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 SGD PMID 10419517
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